In the wake of a solar flare of unusual properties, a mismatched group of inner-city survivors must put aside their animosity to escape a Los Angeles now free of gangbangers, but infested instead with blood-sucking zombies.
After 30 years in a cell for the mentally ill, Ze do Caixao (a.k.a. Coffin Joe) is finally freed. Back on the streets, the sadistic gravedigger is set on fulfilling that for which he was imprisoned: find the woman who can give him the perfect child. During his wanderings through the city of Sao Paulo, he leaves behind a trail of horror as he faces unnatural laws and popular beliefs.
